Название книги: Equilibria and Kinetics of Biological Macromolecules


Автор: Prof. Jan Hermans , Prof. Barry Lentz


ISBN: 9781118733769


Издательство: John Wiley & Sons Limited


Год: 2018


Кол-во стр.: 527


Progressively builds a deep understanding of macromolecular behavior
Based on each of the authors' roughly forty years of biophysics research and teaching experience, this text instills readers with a deep understanding of the biophysics of macromolecules. It sets a solid foundation in the basics by beginning with core physical concepts such as thermodynamics, quantum chemical models, molecular structure and interactions, and water and the hydrophobic effect. Next, the book examines statistical mechanics, protein-ligand binding, and conformational stability. Finally, the authors address kinetics and equilibria, exploring underlying theory, protein folding, and stochastic models.
Equilibria and Kinetics of Biological Macromolecules
offers new insights and perspectives on proteins and other macromolecules. The text features coverage of:
Basic theory, applications, and new research findings Related topics in thermodynamics, quantum mechanics, statistical mechanics, and molecular simulations Principles and applications of molecular simulations in a dedicated chapter and interspersed throughout the text Macromolecular binding equilibria from the perspective of statistical mechanics Stochastic processes related to macromolecules Suggested readings at the end of each chapter include original research papers, reviews and monographs, enabling readers to explore individual topics in greater depth. At the end of the text, ten appendices offer refreshers on mathematical treatments, including probability, computational methods, Poisson equations, and defining molecular boundaries.
Equilibria and Kinetics of Biological Macromolecules
is recommended as a graduate-level textbook for biophysics courses and as a reference for researchers who want to strengthen their understanding of macromolecular behavior.